下图来源于一篇Cell文章 ——Clustered Spearman correlation matrix for different RNA-seq replicates for no treatment and KLA 1h,其主旨是比较不同品系小鼠对基因表达和转录因子结合研究的影响差异有多大。图中展示了不同品系小鼠的野生型和KLA处理组基因表达谱Spearman相似性热图。从对角线处的16-宫格可以看出,小鼠品系比处理方式对表达量的影响更大。
原文描述:
Clustered Spearman correlation matrix for different RNA-seq replicates for no treatment and KLA 1h.
原文描述:
Association between differentially abundant OTUs and clinical biomarkers relevant for diabetes in the total group of 268 individuals. The taxa names indicate the lowest taxonomic affiliation available for the OTUs in the Greengenes database.The colour key indicates Spearman’s ρ and the numbers in the cells represent p values <0.05. Spearman’s ρ and associated p values.
原文描述:
Heatmap shows clustering of tumor types based on top 100 most positively correlated gene sets from gene ontology molecular function category for MYC. the heatmap is colored by the normalized enrichment score of a gene set for a tumor type. Gray cells indicate lack of enrichment. Dots below tumor type denote high MYC amplification, while plus signs denote high mRNA expression. Blue lines on the heatmaps mark gene sets corresponding to the canonical MYC signature, orange lines correspond to the non-canonical MYC signature, and yellow lines correspond to neuronal function, found in MYCN only. Tables contain main gene sets found in each cluster category. One asterisk marks a WNT signaling gene set, and two asterisks mark a metabolic gene set.