Biological Information:生物信息(CS)
Biological Information:生物信息(CS)
在计算机科学中，我们可以在理论上整齐地分离信息的传输和处理、硬件和软件以及程序及其输入。这在生物学上要复杂得多，不过，我认为香农的信息概念在生物学中是有用的，尽管它的应用并不像许多人认为的那么简单。事实上，最近发展起来的信息分解理论可以揭示编码与监管或内部和环境信息之间的互补性。我们在此贡献中提出的主要挑战是了解遗传信息和外部因素如何结合以创建生物体，反过来，基因组在进化过程中是如何学会如何利用环境的，以及类似的，编码、调节和空间组织如何在细胞过程中相互作用。
Biological Information
In computer science, we can theoretically neatly separate transmission and processing of information, hardware and software, and programs and their inputs. This is much more intricate in biology, Nevertheless, I argue that Shannon's concept of information is useful in biology, although its application is not as straightforward as many people think. In fact, the recently developed theory of information decomposition can shed much light on the complementarity between coding and regulatory, or internal and environmental information. The key challenge that we formulate in this contribution is to understand how genetic information and external factors combine to create an organism, and conversely, how the genome has learned in the course of evolution how to harness the environment, and analogously, how coding, regulation and spatial organization interact in cellular processes.
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