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PSM 重打分介绍

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发布于 2025-12-27 16:11:38

发布于 2025-12-27 16:11:38

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概述

《Rescoring Peptide Spectrum Matches: Boosting Proteomics Performance by Integrating Peptide Property Predictors Into Peptide Identification》

文章被收录于专栏：生物医药生物医药

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Highlights

Abstract

Post-Processor Rescoring
- Workflow
- Post-Processor Rescoring Tools
  - PeptideProphet
  - Percolator
  - Barista
  - Nokoi
  - Scavenger
  - Mokapot

Data-Driven Rescoring Pipelines
- Workflow
- Prominent Data-Driven Rescoring Pipelines
  - DeepRescore
  - INFERYS Rescoring
  - MS2Rescore
  - AlphaPeptDeep
  - InSPIRE
  - DeepSCP
  - Oktoberfest
  - MSBooster
- Data-Driven-Like Rescoring Pipelines
  - CharmeRT
  - MS-Rescue
  - MHCquant
  - DART-ID

Future Perspective
- Data-Driven Rescoring vs. Predicted Spectral Library Searching
- 基于数据的重新评分与预测光谱库搜索
- Limitations and Opportunities of Data-Driven Rescoring
- Novel Predictors to Further Boost Performance
- New Frontiers in ML-Guided Feature Generation ML 引导的特征生成新前沿

结论