问Nginx 重新加载失败 ？

nginx: [emerg] BIO_new_file("/etc/nginx/1_www.example.com_bundle.crt") failed (SSL: error:02001002:system library:fopen:No such file or directory:fopen('/etc/nginx/1_www.example.com_bundle.crt','r') error:2006D080:BIO routines:BIO_new_file:no such file)