CAS:2382896-07-1
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性:Sibeprenlimab (VIS649) 是一种人源化 IgG2 单克隆抗体。Sibeprenlimab 可以抑制 APRIL。Sibeprenlimab 可用于 IgA 肾病(IgAN)的研究。
参考详情: https://www.medchemexpress.com/sibeprenlimab.html
参考文献:
[1]. Mohit Mathur, et al. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgG2 Monoclonal Antibody, in Healthy Volunteers. Kidney Int Rep. 2022 Feb 8;7(5):993-1003.
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