问每个进程只能初始化一次CEF。这是底层的限制。

EN

namespace CefSharp.MinimalExample.WinForms
{
    public static class Program
    {
        [STAThread]
        public static int Main(string[] args)
        {
            // Programmatically enable DPI Aweness
            // Can also be done via app.manifest or app.config
            // https://github.com/cefsharp/CefSharp/wiki/General-Usage#high-dpi-displayssupport
            // If set via app.manifest this call will have no effect.
            Cef.EnableHighDPISupport();

            var settings = new CefSettings()
            {
                //By default CefSharp will use an in-memory cache, you need to specify a Cache Folder to persist data
                CachePath = Path.Combine(Environment.GetFolderPath(Environment.SpecialFolder.LocalApplicationData), "CefSharp\\Cache")
            };
       
            Cef.Initialize(settings, performDependencyCheck: true, browserProcessHandler: null);

            var browser = new BrowserForm();
            Application.Run(browser);

            return 0;
        }
    }
}

     Application.EnableVisualStyles();
        Application.SetCompatibleTextRenderingDefault(false);
        CefSettings settings = new CefSettings();
        settings.Locale = "tr";
        settings.CefCommandLineArgs.Add("ppapi-flash-path", "pepflashplayer.dll");
        settings.CefCommandLineArgs.Add("ppapi-flash-version", "99.0.0.999");
        settings.CachePath = Path.Combine(Environment.GetFolderPath(Environment.SpecialFolder.ApplicationData), "Demon Slayer 3");
        Cef.Initialize(settings);
        Form2 frm = new Form2();
        frm.Tabs.Add(new EasyTabs.TitleBarTab(frm)
        {
            Content = new Form1
            {
                Text = "Yeni Sekme"
            }
        }
        );
        frm.SelectedTabIndex= 0;
        TitleBarTabsApplicationContext applicationContext= new TitleBarTabsApplicationContext();
        applicationContext.Start(frm); 
        Application.Run(applicationContext);