如何从特定字符串中消除子字符串

original_str = "This is a sample string with a sample substring."
substring = "sample"
new_str = original_str.replace(substring, "")
print(new_str)

import re

original_str = "This is a sample string with a sample substring."
substring = "sample"
new_str = re.sub(substring, "", original_str)
print(new_str)

original_str = "This is a sample string with multiple sample substrings."
substrings = ["sample", "string"]
new_str = original_str
for substring in substrings:
    new_str = new_str.replace(substring, "")
print(new_str)

original_str = "This is a sample string with multiple sample substrings."
substrings = ["sample", "multiple"]
special_char = " "
for substring in substrings:
    new_str = original_str.replace(substring, special_char)
original_str = new_str.replace(special_char, "")
print(new_str)