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同步升压 5V转8.4V USB连接 锂电池充电线移动电源路由器

General DescriptionThe AP8660 is a current mode boost DC-DC converter. Its PWM circuitry with built-in 0.25Ωpower MOSFET make this regulator highly power efficient. The internal compensation network also minimizes as much as 6 external component counts. The non-inverting input of error amplifier connects to a 0.6V precision reference voltage and internal soft-start function can reduce the inrush current.The AP8660 is available in the SOT23-6L package and provides space-saving PCB for the application fields.Features Adjustable Output up to 24V Internal Fixed PWM frequency: 1.0MHz Precision Feedback Reference Voltage: 0.6V (±2%) Internal 0.25Ω, 2A, 26V Power MOSFET Shutdown Current: 0.1μA Over Voltage Protection Over Temperature Protection Adjustable Over Current Protection: 0.5A ~ 2.5A Package: SOT23-6LApplications Chargers LCD Displays Digital Cameras Handheld Devices Portable Products

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支持12V 1.5A 1A光猫K2路由器电源

General DescriptionThe AP8660 is a current mode boost DC-DC converter. Its PWM circuitry with built-in 0.25Ωpower MOSFET make this regulator highly power efficient. The internal compensation network also minimizes as much as 6 external component counts. The non-inverting input of error amplifier connects to a 0.6V precision reference voltage and internal soft-start function can reduce the inrush current.The AP8660 is available in the SOT23-6L package and provides space-saving PCB for the application fields.Features Adjustable Output up to 24V Internal Fixed PWM frequency: 1.0MHz Precision Feedback Reference Voltage: 0.6V (±2%) Internal 0.25Ω, 2A, 26V Power MOSFET Shutdown Current: 0.1μA Over Voltage Protection Over Temperature Protection Adjustable Over Current Protection: 0.5A ~ 2.5A Package: SOT23-6LApplications Chargers LCD Displays Digital Cameras Handheld Devices Portable Products

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湖北医药学院李童斐教授团队《J. Nanobiotech》:装载双氢青蒿素的纳米反应器用于靶向治疗恶性肿瘤取得新进展

湖北医药学院基础医学院李童斐课题组利用肿瘤微环境响应的铁基金属有机框架(MOF)负载双氢青蒿素(DHA)构建了一种协同诱导铁死亡的纳米反应器(DHA@MIL-101)。DHA@MIL-101在肺癌微环境崩塌。一方面,释放的铁离子与DHA独有的过氧桥化学结构触发类芬顿反应。与此同时,DHA促进转铁蛋白受体表达及抑制谷胱甘肽过氧化物酶(GPX4)的效应进一步促进了该纳米反应器驱动的化学动力学及铁死亡效应,导致DNA及线粒体损伤发挥抗肿瘤疗效。相关成果“A nanoreactor boosts chemodynamic therapy and ferroptosis forsynergistic cancer therapy using molecular amplifier dihydroartemisinin”发表在纳米生物学领域国际知名杂志《Journal of Nanobiotechnology》(IF=10.435, DOI: 10.1186/s12951-022-01455-0)

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