CAS:615258-40-7
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性: Denosumab 是一种人单克隆抗体,可结合并抑制 RANKL (TNFSF11) 的受体激活剂。 Denosumab 可以降低脊椎、非脊椎和髋部骨折的风险[1],还具有抗癌活性[2]。
参考详情:https://www.medchemexpress.cn/denosumab.html
参考文献:
[1]. Moen MD, et al. Denosumab: a review of its use in the treatment of postmenopausal osteoporosis. Drugs Aging. 2011;28(1):63-82.
[2]. Chawla S, et al. Denosumab in patients with giant-cell tumour of bone: a multicentre, open-label, phase 2 study. Lancet Oncol. 2019;20(12):1719-1729.
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