CAS:1875032-68-0
品牌:MedChemExpress (MCE)
存储条件:Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性:Loncastuximab (RB4v1.2) 是一种抗 CD19 单克隆抗体。Loncastuximab 展现出抗肿瘤性,在非霍奇金淋巴瘤 (NHL) 包括弥漫性大 B 细胞淋巴瘤 (DLBCL) 中也有潜在的应用。
参考详情: http://www.medchemexpress.cn/loncastuximab.html
参考文献:
[1]. Zinzani PL, et al. Anti-CD19 monoclonal antibodies for the treatment of relapsed or refractory B-cell malignancies: a narrative review with focus on diffuse large B-cell lymphoma. J Cancer Res Clin Oncol. 2022 Jan;148(1):177-190.
[2]. Hess B, et al. Efficacy and Safety Exposure-Response Analysis of Loncastuximab Tesirine in Patients with B cell non-Hodgkin Lymphoma. AAPS J. 2021 Dec 10;24(1):11.
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